The strike was called off about 2 weeks ago now. whoop whoop! So everything has been
happening so fast, I’ve been keeping busy with going to clinics while trying to
complete all the paperwork that needs to be submitted for the approval of my
research study.
Sickle cell disease and trait is very prevalent in Nigeria,
thus my selection of the country to conduct my research. The country has made
great pushes towards an initiative promoting the knowing of your genotype, as a result many
people before they get married, test to decide whether or not they have the
trait, the goal is to prevent or at least reduce the number of sickle cell
disease births in the country. Knowing your genotype allows people to understand the risks and
likelihood of having a child with the disease. Whether a couple decides to
proceed with a relationship/marriage after they know they both have the trait
is up to them, however armed with the information, they are able to plan for
the best and worst case scenarios.
While at the sickle cell clinic I have noticed an alarming
trend among some of the mothers that presented with their child. Incorrect
genotyping! Out of the approximately forty patients seen thus far with Dr. Ojo
in clinic, four people have said that they were tested as AA (you do not have
sickle cell trait) earlier in their lifetime, and so it was a shock when they
had their child present with sickle cell pain crisis. Four out of forty is a
rate of 10%!!! A lab error rate of 10% is horrendous and unreal! A resounding theme
among the four women was that the issue initially brought on marital problems,
and accusations of infidelity.
It wasn’t until a lot of persuasion and counseling
their husbands agreed to do another genotyping exam along with the mothers and in some cases paternity tests. In these four cases after their genotypes were tested again, they were found to be AS (Sickle cell trait carriers).
It wasn’t until a lot of persuasion and counseling
their husbands agreed to do another genotyping exam along with the mothers and in some cases paternity tests. In these four cases after their genotypes were tested again, they were found to be AS (Sickle cell trait carriers).
Due to this revelation, I have decided to somewhat change the focus of my research, because I believe this topic is an important story to
tell. The hope is to shed light on the growing issue of lab error/genotype
inaccuracy most notably in private hospitals, and hopefully propose solutions
to this issue. This change in my research, will now prolong the already never
ending paper work, but I think it’s well worth the hassle.